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Human ITPRIPL1 Recombinant Protein (C-His)
Key Features

Human ITPRIPL1 Recombinant Protein (C-His) (GXRP10491)

SKU GXRP10491
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag C-His
€347 - €1,827

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Description

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Human ITPRIPL1 Recombinant Protein (C-His)

Human ITPRIPL1 Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Glu125-Pro555, with a C-terminal His tag. Predicted molecular weight: 50.27 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1 is a ~63 kDa protein. Functions as a ligand of CD3E, inhibiting TCR-CD3 complex signaling to regulate T cell activation. For research use only.

Induces stable CD3E-NCK1 binding, thereby preventing the CD3E-ZAP70 interaction and subsequently inhibiting the activation of the downstream ERK-NFkB signaling cascade and calcium influx.

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