Description
Human KDM4B Recombinant Protein (N-His)
Human KDM4B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met16-Asp338, with an N-terminal His tag. Predicted molecular weight: 39.54 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Lysine-specific demethylase 4B (KDM4B) is a ~121 kDa protein. Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. For research use only.
Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. Plays a critical role in the development of the central nervous system (CNS).
| Product Name: | Human KDM4B Recombinant Protein (N-His) |
| SKU: | GXRP07455 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Lysine-specific demethylase 4B, 1.14.11.66, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, [histone H3]-trimethyl-L-lysine(9) demethylase 4B, KDM4B, JHDM3B, JMJD2B, KIAA0876 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met16-Asp338 |
| Calculated MW: | 39.54 kDa |
| UniProt: | O94953 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
