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Human KHDRBS1 Recombinant Protein (N-His)
Key Features

Human KHDRBS1 Recombinant Protein (N-His) (GXRP05070)

SKU GXRP05070
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human KHDRBS1 Recombinant Protein (N-His)

Human KHDRBS1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys111-Gly276, with an N-terminal His tag. Predicted molecular weight: 21.26 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1) is a ~48 kDa protein. Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. For research use only.

Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.

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