Description
Human KMT2D Recombinant Protein (N-His)
Human KMT2D Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val5381-Met5536, with an N-terminal His tag. Predicted molecular weight: 20.71 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Histone-lysine N-methyltransferase 2D (KMT2D) is a ~593 kDa protein. Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4). For research use only.
Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.
| Product Name: | Human KMT2D Recombinant Protein (N-His) |
| SKU: | GXRP04580 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | KMT2D, Histone-lysine N-methyltransferase 2D, Myeloid/lymphoid or mixed-lineage leukemia protein 2, ALL1-related protein, MLL4, ALR, Lysine N-methyltransferase 2D, MLL2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Val5381-Met5536 |
| Calculated MW: | 20.71 kDa |
| UniProt: | O14686 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
