Description
Human LAMB1 Recombinant Protein (N-His)
Human LAMB1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe549-His767, with an N-terminal His tag. Predicted molecular weight: 27.16 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Laminin subunit beta-1 (LAMB1) is a ~198 kDa protein. Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. For research use only.
Involved in the organization of the laminar architecture of the cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface. As a subunit of laminin-1 (also known as laminin-111 or EHS laminin), it is involved in the stimulation of agrin-induced receptor clustering through a MuSK-independent pathway.
| Product Name: | Human LAMB1 Recombinant Protein (N-His) |
| SKU: | GXRP00686 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Laminin-1 subunit beta, Laminin-8 subunit beta, Laminin-2 subunit beta, Laminin-6 subunit beta, Laminin-10 subunit beta, Laminin B1 chain, Laminin subunit beta-1, LAMB1, Laminin-12 subunit beta, laminin-1, laminin-111, EHS laminin, laminin-2, laminin-211, merosin, laminin-6, laminin-311, K-laminin, laminin-8, laminin-411, laminin-10, laminin-511, laminin-12, laminin-213 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Phe549-His767 |
| Calculated MW: | 27.16 kDa |
| UniProt: | P07942 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
