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Human LAT ELISA Kit

SKU:
HUFI02597
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O43561
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich ELISA, Double Antibody
Synonyms:
LAT, 36 kDa phospho-tyrosine adapter protein, pp36, pp36, 36 kDa phospho-tyrosine adapter protein, LAT1, 36 kDa phospho-tyrosine adaptor protein, linker for activation of T cells, linker for activation of T-cells family member 1, p36-38
Reactivity:
Human
€599
Frequently bought together:

Description

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Human LAT ELISA Kit

LAT (Linker For Activation Of T Cells) is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. LAT is a transmembrane protein that localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. LAT recruits multiple adaptor proteins and downstream signaling molecules at the site of TCR engagement. Mutations in LAT are associated with immunodeficiency.