Description
Human LAT Recombinant Protein (N-His)
Human LAT Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu25-Val221, with an N-terminal His tag. Predicted molecular weight: 23.27 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Linker for activation of T-cells family member 1 (LAT) is a ~27 kDa protein. Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. For research use only.
Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
| Product Name: | Human LAT Recombinant Protein (N-His) |
| SKU: | GXRP00166 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | pp36, 36 kDa phospho-tyrosine adapter protein, Linker for activation of T-cells family member 1, LAT, p36-38 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu25-Val221 |
| Calculated MW: | 23.27 kDa |
| UniProt: | O43561 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
