Description
Human LDLR Recombinant Protein (N-His)
Human LDLR Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr497-Thr742, with an N-terminal His tag. Predicted molecular weight: 29.53 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Low-density lipoprotein receptor (LDLR) is a ~95 kDa protein. Binds low density lipoprotein /LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. For research use only.
In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Forms a ternary complex with PGRMC1 and TMEM97 receptors which increases LDLR-mediated LDL internalization.
| Product Name: | Human LDLR Recombinant Protein (N-His) |
| SKU: | GXRP00402 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | LDLR, Low-density lipoprotein receptor, LDL receptor |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr497-Thr742 |
| Calculated MW: | 29.53 kDa |
| UniProt: | P01130 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
