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Human LEF1 Recombinant Protein (N-His)
Key Features

Human LEF1 Recombinant Protein (N-His) (GXRP03044)

SKU GXRP03044
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human LEF1 Recombinant Protein (N-His)

Human LEF1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu45-His260, with an N-terminal His tag. Predicted molecular weight: 25.63 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Lymphoid enhancer-binding factor 1 (LEF1) is a ~44 kDa protein. Transcription factor that binds DNA in a sequence-specific manner. For research use only.

Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1.

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