Description
Human LETMD1 Recombinant Protein (N-His)
Human LETMD1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Pro162-Asn347, with an N-terminal His tag. Predicted molecular weight: 23.69 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. LETM1 domain-containing protein 1 (LETMD1) is a ~41 kDa protein. Plays an essential role for mitochondrial structure and function, as well as thermogenesis of brown adipocytes. For research use only.
In brown adipose tissue also localizes in the nucleus where it interacts with the chromatin remodeler SMARCA4 to regulate thermogenic genes expression, such as UCP1. May regulate phagocytosis and inflammatory responses to lipopolysaccharide in macrophages. Involved in tumorigenesis and may function as a negative regulator of the p53/TP53.
| Product Name: | Human LETMD1 Recombinant Protein (N-His) |
| SKU: | GXRP02458 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | HCCR-1, Cervical cancer proto-oncogene 2 protein, Cervical cancer 1 proto-oncogene protein p40, HCRR-2, LETMD1, LETM1 domain-containing protein 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Pro162-Asn347 |
| Calculated MW: | 23.69 kDa |
| UniProt: | Q6P1Q0 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
