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Human LIPC Recombinant Protein (N-His)
Key Features

Human LIPC Recombinant Protein (N-His) (GXRP00863)

SKU GXRP00863
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human LIPC Recombinant Protein (N-His)

Human LIPC Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu47-Pro478, with an N-terminal His tag. Predicted molecular weight: 50.6 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Hepatic triacylglycerol lipase (LIPC) is a ~55 kDa protein. Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles. For research use only.

Also exhibits lysophospholipase activity. Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrates. In native LDL, preferentially hydrolyzes the phosphatidylcholine species containing polyunsaturated fatty acids at sn-2 position.

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