Description
Human LMTK3 Recombinant Protein (N-His)
Human LMTK3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln116-Pro416, with an N-terminal His tag. Predicted molecular weight: 36.97 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Serine/threonine-protein kinase LMTK3 is a ~153 kDa protein. Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. For research use only.
May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription. Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons.
| Product Name: | Human LMTK3 Recombinant Protein (N-His) |
| SKU: | GXRP12224 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | EC:2.7.11.1, KIAA1883, LMTK3, Lemur tyrosine kinase 3, Serine/threonine-protein kinase LMTK3, TYKLM3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gln116-Pro416 |
| Calculated MW: | 36.97 kDa |
| UniProt: | Q96Q04 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
