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Human LRP2 ELISA Kit

SKU:
HUFI00500
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P98164
Sensitivity:
0.469ng/ml
Range:
0.781-50ng/ml
ELISA Type:
Sandwich
Synonyms:
LRP2, gp330, Megalin, LRP-2, Low-density lipoprotein receptor-related protein 2, Glycoprotein 330
Reactivity:
Human
Research Area:
Cell Biology
€599
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Description

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Human LRP2 ELISA Kit

LRP2 (LDL Receptor Related Protein 2) is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. LRP2 glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. LRP2 has a role in cell-signaling and is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. Mutations in LRP2 cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).