Description
Human LTBP1 Recombinant Protein (N-His)
Human LTBP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu876-Asp1315, with an N-terminal His tag. Predicted molecular weight: 50.40 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Latent-transforming growth factor beta-binding protein 1 is a ~186 kDa protein. Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. For research use only.
Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta.
| Product Name: | Human LTBP1 Recombinant Protein (N-His) |
| SKU: | GXRP10893 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | LTBP-1, LTBP1, Latent-transforming growth factor beta-binding protein 1, TGF-beta1-BP-1, Transforming growth factor beta-1-binding protein 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu876-Asp1315 |
| Calculated MW: | 50.40 kDa |
| UniProt: | Q14766 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
