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Human LY6G6D/MEGT1 (1G4) Antibody - SDS-PAGE
Key Features

Human LY6G6D/MEGT1 (1G4) Antibody (GXBS02017)

Datasheet MSDS
SKU GXBS02017
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Human
Reactivity Human
Applications ELISA, FACS, Functional assay, Research in vivo
Clone ID 1G4
Isotype IgG1
$616 - $1,965

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Description

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Human LY6G6D/MEGT1 (1G4) Antibody

Human LY6G6D/MEGT1 (1G4) Antibody is a research-grade biosimilar monoclonal antibody. It is a human IgG1 antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Product Name:Human LY6G6D/MEGT1 (1G4) Antibody
SKU:GXBS02017
Size:100 µg, 1 mg
Antibody Type:Monoclonal Antibody
Clone:1G4
Target:MEGT1
Isotype:IgG1
Host Species:Human
Reactivity:Human
Applications:ELISA, FACS, Functional assay, Research in vivo
Expression Host:Mammalian cells
Synonyms:MEGT1, G6D, Megakaryocyte-enhanced gene transcript 1 protein, NG25, LY6G6D, C6orf23, Protein Ly6-D, Lymphocyte antigen 6 complex locus protein G6d
Biological Activity:NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC 50 s of 149 nM and 21.7 nM, respectively. NG25 also potently suppresses several kinases such as LYN, CSK, FER, p38α, ABL,ARG and SRC, with IC 50 s of 12.9, 56.4, 82.3, 102, 75.2, and 113 nM, respectively [1]. NG25 is very potent suppressor of CpG B- or CpG A-stimulated secretion of IFNα and CL097-stimulated secretion of IFNβ, with complete inhibition by 400 nM [2]. NG25 treatment reduces cell viability of all tested breast cancer cell lines in a dose dependent manner. NG25 (2?uM) enhances the cytotoxic effect of Dox on breast cancer cells [3].
Purity:>95% purity as determined by SDS-PAGE.
Endotoxin Level:< 10 EU/mg
Formulation:0.01M PBS pH 7.4
State of Matter:Liquid
Regulatory Status:For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:Protein A/G purified from cell culture supernatant.
Storage and Handling:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
UniProt:O95868
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