Description
Human LYNX1 Recombinant Protein (N-His)
Human LYNX1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu21-Leu116, with an N-terminal His tag. Predicted molecular weight: 12.85 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Ly-6/neurotoxin-like protein 1 is a ~12 kDa protein. Acts in different tissues through interaction to nicotinic acetylcholine receptors (nAChRs). For research use only.
The proposed role as modulator of nAChR activity seems to be dependent on the nAChR subtype and stoichiometry, and to involve an effect on nAChR trafficking and its cell surface expression, and on single channel properties of the nAChR inserted in the plasma membrane. Modulates functional properties of nicotinic acetylcholine receptors (nAChRs) to prevent excessive excitation, and hence neurodegeneration. Enhances desensitization by increasing both the rate and extent of desensitization of alpha-4:beta-2-containing nAChRs and slowing recovery from desensitization. Promotes large amplitude ACh-evoked currents through alpha-4:beta-2 nAChRs.
| Product Name: | Human LYNX1 Recombinant Protein (N-His) |
| SKU: | GXRP11263 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Endogenous prototoxin LYNX1, LYNX1, Ly-6/neurotoxin-like protein 1, Testicular tissue protein Li 112 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu21-Leu116 |
| Calculated MW: | 12.85 kDa |
| UniProt: | P0DP58 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
