Description
Human MACF1 Recombinant Protein (N-His)
Human MACF1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg7114-Lys7387, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 is a ~838 kDa protein. F-actin-binding protein which plays a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. For research use only.
Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. Interaction with CAMSAP3 at the minus ends of non-centrosomal microtubules tethers microtubules minus-ends to actin filaments, regulating focal adhesion size and cell migration.
| Product Name: | Human MACF1 Recombinant Protein (N-His) |
| SKU: | GXRP13732 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 620 kDa actin-binding protein, ABP620, ACF7, Actin cross-linking family protein 7, KIAA0465, KIAA0754, KIAA1251, MACF1, Macrophin-1, Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5, Trabeculin-alpha |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg7114-Lys7387 |
| UniProt: | Q9UPN3 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
