Description
Human MAEA Recombinant Protein (N-His)
Human MAEA Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Cys136-Pro379, with an N-terminal His tag. Predicted molecular weight: 30.2 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. E3 ubiquitin-protein transferase MAEA is a ~45 kDa protein. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. For research use only.
MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1. Plays a role in erythroblast enucleation during erythrocyte maturation and in the development of mature macrophages.
| Product Name: | Human MAEA Recombinant Protein (N-His) |
| SKU: | GXRP02494 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | HLC-10, E3 ubiquitin-protein transferase MAEA, Erythroblast macrophage protein, Cell proliferation-inducing gene 5 protein, P44EMLP, MAEA, Human lung cancer oncogene 10 protein, EMP, Macrophage erythroblast attacher |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Cys136-Pro379 |
| Calculated MW: | 30.2 kDa |
| UniProt: | Q7L5Y9 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
