Description
Human MAGEC2 Recombinant Protein (N-His)
Human MAGEC2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp132-Ser328, with an N-terminal His tag. Predicted molecular weight: 24.81 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Melanoma-associated antigen C2 (MAGEC2) is a ~41 kDa protein. Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. For research use only.
In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.
| Product Name: | Human MAGEC2 Recombinant Protein (N-His) |
| SKU: | GXRP04756 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | MAGEC2, MAGEE1, HCA587, Cancer/testis antigen 10, MAGE-C2 antigen, MAGE-E1 antigen, CT10, Melanoma-associated antigen C2, Hepatocellular carcinoma-associated antigen 587 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp132-Ser328 |
| Calculated MW: | 24.81 kDa |
| UniProt: | Q9UBF1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
