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Human MAP2K7 Recombinant Protein (N-His)
Key Features

Human MAP2K7 Recombinant Protein (N-His) (GXRP03347)

SKU GXRP03347
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human MAP2K7 Recombinant Protein (N-His)

Human MAP2K7 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr103-Arg419, with an N-terminal His tag. Predicted molecular weight: 38.97 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7) is a ~47 kDa protein. Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. For research use only.

Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K4/MKK4, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue.

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