Description
Human MAP3K5 Recombinant Protein (N-His)
Human MAP3K5 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly681-Glu936, with an N-terminal His tag. Predicted molecular weight: 30.82 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is a ~154 kDa protein. Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. For research use only.
Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens.
| Product Name: | Human MAP3K5 Recombinant Protein (N-His) |
| SKU: | GXRP02771 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ASK1, MAPK/ERK kinase kinase 5, MEKK5, MAPKKK5, MEKK 5, Apoptosis signal-regulating kinase 1, ASK-1, Mitogen-activated protein kinase kinase kinase 5, MAP3K5, MEK kinase 5 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly681-Glu936 |
| Calculated MW: | 30.82 kDa |
| UniProt: | Q99683 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
