Description
Human MAPK9 Recombinant Protein (N-His)
Human MAPK9 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Tyr26-Ile321, with an N-terminal His tag. Predicted molecular weight: 36.28 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Mitogen-activated protein kinase 9 (MAPK9) is a ~48 kDa protein. Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. For research use only.
Extracellular stimuli such as pro-inflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK9/JNK2. In turn, MAPK9/JNK2 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. In response to oxidative or ribotoxic stresses, inhibits rRNA synthesis by phosphorylating and inactivating the RNA polymerase 1-specific transcription initiation factor RRN3.
| Product Name: | Human MAPK9 Recombinant Protein (N-His) |
| SKU: | GXRP01633 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Mitogen-activated protein kinase 9, MAPK 9, Stress-activated protein kinase 1a, SAPK1A, MAP kinase 9, SAPK1a, Stress-activated protein kinase JNK2, PRKM9, JNK-55, MAPK9, JNK2, c-Jun N-terminal kinase 2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Tyr26-Ile321 |
| Calculated MW: | 36.28 kDa |
| UniProt: | P45984 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
