Description
Human MBIP Recombinant Protein (N-His)
Human MBIP Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys153-Gly300, with an N-terminal His tag. Predicted molecular weight: 18.98 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. MAP3K12-binding inhibitory protein 1 (MBIP) is a ~39 kDa protein. Functions as part of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. For research use only.
Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Together with MOCS2B, inhibits the activity of stress kinase EIF2AK2/PKR; this may lead to effects such as suppression of JNK activation and subsequent stress-responsive transcription, or suppression of eIF2a phosphorylation to favor translation.
| Product Name: | Human MBIP Recombinant Protein (N-His) |
| SKU: | GXRP07646 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | MAP3K12-binding inhibitory protein 1, MAPK upstream kinase-binding inhibitory protein, MUK-binding inhibitory protein, MBIP, BM-015 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Lys153-Gly300 |
| Calculated MW: | 18.98 kDa |
| UniProt: | Q9NS73 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
