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Human MEF2C Recombinant Protein (N-His-SUMO & C-Strep)
Key Features

Human MEF2C Recombinant Protein (N-His-SUMO & C-Strep) (GXRP04131)

SKU GXRP04131
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His-SUMO & C-Strep
$458 - $2,412

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Description

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Human MEF2C Recombinant Protein (N-His-SUMO & C-Strep)

Human MEF2C Recombinant Protein (N-His-SUMO & C-Strep) is a recombinant protein expressed in E. coli, spanning Arg10-Gly95, with an N-terminal His-SUMO tag and a C-terminal Strep tag. Predicted molecular weight: 23.74 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Myocyte-specific enhancer factor 2C (MEF2C) is a ~51 kDa protein. Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. For research use only.

Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex.

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