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Human MGAT3 Recombinant Protein (N-His)
Key Features

Human MGAT3 Recombinant Protein (N-His) (GXRP09648)

SKU GXRP09648
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human MGAT3 Recombinant Protein (N-His)

Human MGAT3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser87-Val533, with an N-terminal His tag. Predicted molecular weight: 53.85 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase is a ~61 kDa protein. It is involved in the regulation of the biosynthesis and biological function of glycoprotein oligosaccharides. For research use only.

Catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains, called bisecting N-acetylglucosamine (GlcNAc). It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. The addition of this bisecting GlcNAc residue alters not only the composition, but also the conformation of the N-glycan. The introduction of the bisecting GlcNAc residue results in the suppression of further processing and elongation of N-glycans, precluding the formation of beta-1,6 GlcNAc branching, catalyzed by MGAT5 since it is unable to use the bisected oligosaccharide as a substrate.

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