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Human MGP (Matrix Gla Protein) ELISA Kit

SKU:
HUFI01361
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P08493
Sensitivity:
9.375pg/ml
Range:
15.625-1000pg/ml
ELISA Type:
Sandwich ELISA, Double Antibody
Synonyms:
MGP, Matrix Gla Protein, Cell growth-inhibiting gene 36 protein
Reactivity:
Human
€599
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Description

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Human MGP (Matrix Gla Protein) ELISA Kit

MGP belongs to the osteocalcin/matrix Gla family. Chondrocytes and vascular smooth muscle cells secrete MGP, which acts as a physiological inhibitor of ectopic tissue calcification. MGP carboxylation status is linked to calcification of the vasculature in cardiovascular disease patients and calcification of the synovial membranes in osteoarthritis patients. Keutel syndrome, peripheral pulmonary stenosis, and facial hypoplasia are linked to mutations in MGP. Warfarin Pathway, and Validated transcriptional targets of AP1 family members Fra1 and Fra2 are among MGP related pathways.