Description
Human MGRN1 Recombinant Protein (N-His)
Human MGRN1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp16-Gln251, with an N-terminal His tag. Predicted molecular weight: 29.07 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. E3 ubiquitin-protein ligase MGRN1 is a ~60 kDa protein. E3 ubiquitin-protein ligase. For research use only.
Mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. Plays a role in the regulation of endosome-to-lysosome trafficking. Impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production. Does not inhibit ADRB2-signaling.
| Product Name: | Human MGRN1 Recombinant Protein (N-His) |
| SKU: | GXRP04443 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | KIAA0544, RING finger protein 156, RNF156, Mahogunin RING finger protein 1, E3 ubiquitin-protein ligase MGRN1, MGRN1, RING-type E3 ubiquitin transferase MGRN1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asp16-Gln251 |
| Calculated MW: | 29.07 kDa |
| UniProt: | O60291 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
