Description
Human MMP2 Recombinant Protein (N-His)
Human MMP2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Tyr110-Cys660, with an N-terminal His tag. Predicted molecular weight: 64.35 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. 72 kDa type IV collagenase (MMP2) is a ~73 kDa protein. Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. For research use only.
As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta.
| Product Name: | Human MMP2 Recombinant Protein (N-His) |
| SKU: | GXRP00712 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 72 kDa gelatinase, Matrix metalloproteinase-2, Gelatinase A, TBE-1, MMP2, CLG4A, 72 kDa type IV collagenase, MMP-2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Tyr110-Cys660 |
| Calculated MW: | 64.35 kDa |
| UniProt: | P08253 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
