Description
Human MMP24 Recombinant Protein (N-His)
Human MMP24 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ile379-Trp566, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Matrix metalloproteinase-24 is a ~73 kDa protein. Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. For research use only.
Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence. May play a role in axonal growth. Able to activate progelatinase A.
| Product Name: | Human MMP24 Recombinant Protein (N-His) |
| SKU: | GXRP13253 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | EC:3.4.24.-, MMP-24, MMP24, MT-MMP 5, MT5-MMP, MT5MMP, MTMMP5, Matrix metalloproteinase-24, Membrane-type matrix metalloproteinase 5, Membrane-type-5 matrix metalloproteinase, Processed matrix metalloproteinase-24 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ile379-Trp566 |
| UniProt: | Q9Y5R2 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
