Matrix metalloproteinase-7 proenzyme (proMMP-7) is a 30.47 kDa matrix metalloproteinases with 273 amino acid residues. MMP-7 restricted production by normal mucosal and exocrine gland epithelial cells, as well as by carcinoma cells. Functionally, it involved breakdown of extracellular matrix (casein, gelatins of types I, III, IV, and V, and fibronecti n) in normal physiological processes and disease processes. MMP-7 is contributed to early tumor development during carcinogenesis. proMMP7 activation by trypsin occurs via an intermediate cleaved at Lys50-Asn51.
Product Name:
Recombinant Human MMP7 protein(N-His)
SKU:
RPES6479
Size:
100μg, 20μg
Species:
Human
Synonyms:
MMP-7, MPSL1, PUMP-1
Tag:
C-His
Sequence:
Met 1-Lys 267
Expression Host:
E.coli
Accession:
P09237
Endotoxin:
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Calculated MW:
30.5 kDa
Observed MW:
26 kDa
Bio-Activity:
Not validated for activity
Form:
Lyophilized powder
Source:
E.coli-derived Human MMP7 protein Met 1-Lys 267, with an C-terminal His
Formulation:
Lyophilized from sterile PBS,pH 8.0. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Storage:
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to - 80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
