Description
Human MNAT1 Recombinant Protein (N-His)
Human MNAT1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Ile113, with an N-terminal His tag. Predicted molecular weight: 14.62 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CDK-activating kinase assembly factor MAT1 (MNAT1) is a ~35 kDa protein. Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. For research use only.
CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
| Product Name: | Human MNAT1 Recombinant Protein (N-His) |
| SKU: | GXRP08027 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | p36, MNAT1, MAT1, Menage a trois, Cyclin-G1-interacting protein, RING finger protein MAT1, RING finger protein 66, RNF66, CDK7/cyclin-H assembly factor, p35, CAP35, CDK-activating kinase assembly factor MAT1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Ile113 |
| Calculated MW: | 14.62 kDa |
| UniProt: | P51948 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
