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Human/Mouse/Rat DNAJA1 Recombinant Protein (N-His)
Key Features

Human/Mouse/Rat DNAJA1 Recombinant Protein (N-His) (GXRP05005)

SKU GXRP05005
Product Type Recombinant Protein
Species Rat
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human/Mouse/Rat DNAJA1 Recombinant Protein (N-His)

Human/Mouse/Rat DNAJA1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn106-Asn327, with an N-terminal His tag. Predicted molecular weight: 27.14 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. DnaJ homolog subfamily A member 1 (DNAJA1) is a ~44 kDa protein. Co-chaperone for HSPA8/Hsc70. For research use only.

Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as a co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis. Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV.

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