Description
Human MSH2 Recombinant Protein (N-His)
Human MSH2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu12-Asp295, with an N-terminal His tag. Predicted molecular weight: 33.75 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. DNA mismatch repair protein Msh2 is a ~104 kDa protein. Component of the post-replicative DNA mismatch repair system (MMR). For research use only.
Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long.
| Product Name: | Human MSH2 Recombinant Protein (N-His) |
| SKU: | GXRP05047 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | hMSH2, MutS protein homolog 2, MSH2, DNA mismatch repair protein Msh2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu12-Asp295 |
| Calculated MW: | 33.75 kDa |
| UniProt: | P43246 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
