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Human MTO1 Recombinant Protein (N-His)
Key Features

Human MTO1 Recombinant Protein (N-His) (GXRP09655)

SKU GXRP09655
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human MTO1 Recombinant Protein (N-His)

Human MTO1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala518-Thr675, with an N-terminal His tag. Predicted molecular weight: 20.27 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. 5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial is a ~79 kDa protein. Component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. For research use only.

Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity.

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