Description
Human MUC4 Recombinant Protein (C-His)
Human MUC4 Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Gln5118-Glu5360, with a C-terminal His tag. Predicted molecular weight: 30.30 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Mucin-4 (MUC4) is a ~542 kDa protein. Membrane-bound mucin, a family of highly glycosylated proteins that constitute the major component of the mucus, the slimy and viscous secretion covering epithelial surfaces. For research use only.
These glycoproteins play important roles in the protection of the epithelium and are implicated in epithelial renewal and differentiation. Regulates cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and its ability to act as an intramembrane ligand for ERBB2. Plays an important role in proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. In polarized epithelial cells, segregates ERBB2 and other ERBB receptors and prevents ERBB2 from acting as a coreceptor.
| Product Name: | Human MUC4 Recombinant Protein (C-His) |
| SKU: | GXRP07881 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | MUC-4, Ascites sialoglycoprotein 1, Ascites sialoglycoprotein 2, ASGP-1, ASGP-2, Testis mucin, MUC4, Ascites sialoglycoprotein, Pancreatic adenocarcinoma mucin, ASGP, Tracheobronchial mucin, Mucin-4 |
| Tag: | C-His |
| Expression Host: | E. coli |
| Protein Length: | Gln5118-Glu5360 |
| Calculated MW: | 30.30 kDa |
| UniProt: | Q99102 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
