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Human MYD88 Recombinant Protein (N-His)
Key Features

Human MYD88 Recombinant Protein (N-His) (GXRP02786)

SKU GXRP02786
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human MYD88 Recombinant Protein (N-His)

Human MYD88 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met157-Pro296, with an N-terminal His tag. Predicted molecular weight: 18.58 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Myeloid differentiation primary response protein MyD88 is a ~33 kDa protein. Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. For research use only.

Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes.

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