Description
Human MYOG Recombinant Protein (N-His-SUMO)
Human MYOG Recombinant Protein (N-His-SUMO) is a recombinant protein expressed in E. coli, spanning Leu66-Gln155, with an N-terminal His-SUMO tag. Predicted molecular weight: 22.81 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Myogenin is a ~25 kDa protein. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. For research use only.
Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast differentiation, plays a role as a strong activator of transcription at loci with an open chromatin structure previously initiated by MYOD1.
| Product Name: | Human MYOG Recombinant Protein (N-His-SUMO) |
| SKU: | GXRP04733 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Myf-4, Myogenin, bHLHc3, BHLHC3, MYOG, MYF4, Myogenic factor 4, Class C basic helix-loop-helix protein 3 |
| Tag: | N-His-SUMO |
| Expression Host: | E. coli |
| Protein Length: | Leu66-Gln155 |
| Calculated MW: | 22.81 kDa |
| UniProt: | P15173 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
