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Human NABP1 Recombinant Protein (N-His)
Key Features

Human NABP1 Recombinant Protein (N-His) (GXRP12003)

SKU GXRP12003
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human NABP1 Recombinant Protein (N-His)

Human NABP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Arg204, with an N-terminal His tag. Predicted molecular weight: 24.59 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. SOSS complex subunit B2 is a ~22 kDa protein. Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. For research use only.

In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

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