Description
Human NANOS2 Recombinant Protein (C-His)
Human NANOS2 Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Met1-Arg138, with a C-terminal His tag. Predicted molecular weight: 16.20 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nanos homolog 2 is a ~15 kDa protein. Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. For research use only.
Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial stem cell population.
| Product Name: | Human NANOS2 Recombinant Protein (C-His) |
| SKU: | GXRP09259 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Nanos homolog 2; NOS-2; NANOS2; NOS2 |
| Tag: | C-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Arg138 |
| Calculated MW: | 16.20 kDa |
| UniProt: | P60321 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
