Description
Human NCAPH2 Recombinant Protein (N-His)
Human NCAPH2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser464-Pro605, with an N-terminal His tag. Predicted molecular weight: 18.75 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Condensin-2 complex subunit H2 is a ~68 kDa protein. Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. For research use only.
May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of chromatin bridges at anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.
| Product Name: | Human NCAPH2 Recombinant Protein (N-His) |
| SKU: | GXRP09611 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Condensin-2 complex subunit H2; Chromosome-associated protein H2; hCAP-H2; Kleisin-beta; Non-SMC condensin II complex subunit H2; NCAPH2; CAPH2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser464-Pro605 |
| Calculated MW: | 18.75 kDa |
| UniProt: | Q6IBW4 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
