Description
Human NCOA3 Recombinant Protein (N-His)
Human NCOA3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly1023-Ala1304, with an N-terminal His tag. Predicted molecular weight: 33.49 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nuclear receptor coactivator 3 (NCOA3) is a ~155 kDa protein. Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. For research use only.
Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.
| Product Name: | Human NCOA3 Recombinant Protein (N-His) |
| SKU: | GXRP03526 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | RAC-3, Class E basic helix-loop-helix protein 42, NCoA-3, Steroid receptor coactivator protein 3, bHLHe42, TRAM-1, ACTR, Receptor-associated coactivator 3, TRAM1, RAC3, BHLHE42, SRC-3, pCIP, Amplified in breast cancer 1 protein, AIB-1, Thyroid hormone receptor activator molecule 1, CBP-interacting protein, AIB1, NCOA3, Nuclear receptor coactivator 3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly1023-Ala1304 |
| Calculated MW: | 33.49 kDa |
| UniProt: | Q9Y6Q9 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
