Description
Human NDE1 Recombinant Protein (N-His)
Human NDE1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe8-Glu187, with an N-terminal His tag. Predicted molecular weight: 23.92 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nuclear distribution protein nudE homolog 1 (NDE1) is a ~37 kDa protein. Required for centrosome duplication and formation and function of the mitotic spindle. For research use only.
Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a postmitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex.
| Product Name: | Human NDE1 Recombinant Protein (N-His) |
| SKU: | GXRP04141 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | NudE, Nuclear distribution protein nudE homolog 1, NUDE, NDE1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Phe8-Glu187 |
| Calculated MW: | 23.92 kDa |
| UniProt: | Q9NXR1 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
