Human NDUFV3 Recombinant Protein (RPPB2017)
- SKU:
- RPPB2017
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P56181
- Research Area:
- Enzymes
Description
| Product Name: | Human NDUFV3 Recombinant Protein |
| Product Code: | RPPB2017 |
| Size: | 20µg |
| Species: | Human |
| Target: | NDUFV3 |
| Synonyms: | NADH Dehydrogenase (Ubiquinone) Flavoprotein 3 10kDa, Renal Carcinoma Antigen NY-REN-4, NADH-Ubiquinone Oxidoreductase 9 KDa Subunit, EC 1.6.5.311, CI-10k, Complex I 10kDa |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The NDUFV3 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.2M NaCl, 2mM DTT, 2mM EDTA and 50% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSSAESGKS EKGQPQNSKK QSPPKKPAPV PAEPFDNTTY KNLQHHDYST YTFLDLNLEL SKFRMPQPSS GRESPRH |
NDUFV3 is one of no less than 41 subunits which form the NADH-ubiquinone oxidoreductase complex that is involved in the mitochondrial respiratory chain and assists in catalyzing the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. NDUFV3 is 1 of 3 proteins found in the flavoprotein fraction of the complex but it exact function is unknown. Two transcript variants encoding altered isoforms are known for this gene.
NDUFV3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 97 amino acids (35-108) and having a molecular mass of 10.8kDa.NDUFV3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | NDUFV3: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFV3 subunit family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Mitochondrial; Oxidoreductase; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: mitochondrial inner membrane; mitochondrial respiratory chain complex I; mitochondrion; nucleoplasm Biological Process: mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly |
| NCBI Summary: | The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P56181 |
| NCBI GenInfo Identifier: | 20178326 |
| NCBI Gene ID: | 4731 |
| NCBI Accession: | P56181.2 |
| UniProt Secondary Accession: | P56181,Q6FGD3, Q8WU60, Q9HCR5, A8K0M1, J3KNX7, |
| UniProt Related Accession: | P56181 |
| Molecular Weight: | 50,984 Da |
| NCBI Full Name: | NADH dehydrogenase |
| NCBI Synonym Full Names: | NADH:ubiquinone oxidoreductase subunit V3 |
| NCBI Official Symbol: | NDUFV3�� |
| NCBI Official Synonym Symbols: | CI-10k; CI-9KD�� |
| NCBI Protein Information: | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial |
| UniProt Protein Name: | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial |
| UniProt Synonym Protein Names: | Complex I-9kD; CI-9kD; NADH-ubiquinone oxidoreductase 9 kDa subunit; Renal carcinoma antigen NY-REN-4 |
| Protein Family: | NADH dehydrogenase [ubiquinone] flavoprotein |
| UniProt Gene Name: | NDUFV3�� |
| UniProt Entry Name: | NDUV3_HUMAN |
