Description
Human NFATC2 Recombinant Protein (N-His)
Human NFATC2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser407-Asn565, with an N-terminal His tag. Predicted molecular weight: 20.12 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nuclear factor of activated T-cells, cytoplasmic 2 (NFATC2) is a ~100 kDa protein. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF or GM-CSF. For research use only.
Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway. Is involved in the negative regulation of chondrogenesis. Recruited by AKAP5 to ORAI1 pore-forming subunit of CRAC channels in Ca(2+) signaling microdomains where store-operated Ca(2+) influx is coupled to calmodulin and calcineurin signaling and activation of NFAT-dependent transcriptional responses.
| Product Name: | Human NFATC2 Recombinant Protein (N-His) |
| SKU: | GXRP04356 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | NFAT pre-existing subunit, NFATc2, Nuclear factor of activated T-cells, cytoplasmic 2, NF-ATc2, T-cell transcription factor NFAT1, NFATC2, NF-ATp, NFAT1, NFATP |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser407-Asn565 |
| Calculated MW: | 20.12 kDa |
| UniProt: | Q13469 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
