Description
Human NME6 Recombinant Protein (N-His)
Human NME6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Leu11-Ala186, with an N-terminal His tag. Predicted molecular weight: 22.38 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nucleoside diphosphate kinase 6, mitochondrial (NME6) is a ~21 kDa protein. Catalytic subunit of a complex with RCC1L, which catalyzes the transfer of a gamma-phosphoryl group from a nucleoside triphosphate, mainly ATP, to a nucleoside diphosphate via a ping-pong mechanism involving the formation of a phosphohistidine intermediate. For research use only.
Participates in the regulation of mitochondrial nucleotide levels, mitoribosome biogenesis, and mitochondrial RNA abundances. Supplies pyrimidine ribonucleoside triphosphates (rNTPs) for mitochondrial transcription and is required for the maintenance of mitochondrial DNA (mtDNA) when the import of pyrimidine deoxyribonucleoside triphosphates (dNTPs) is limited from the cytosol is limited. As a monomer, lacks nucleoside diphosphate kinase (NDPK) activity.
| Product Name: | Human NME6 Recombinant Protein (N-His) |
| SKU: | GXRP00237 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | nm23-H6, Nucleoside diphosphate kinase 6, IPIA-alpha, NME6, NDP kinase 6, Inhibitor of p53-induced apoptosis-alpha, NDK 6 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Leu11-Ala186 |
| Calculated MW: | 22.38 kDa |
| UniProt: | O75414 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
