Description
Human NMI Recombinant Protein (N-His)
Human NMI Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Phe58-Glu307, with an N-terminal His tag. Predicted molecular weight: 30.64 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. N-myc-interactor is a ~35 kDa protein. Acts as a signaling pathway regulator involved in innate immune system response. For research use only.
In response to interleukin 2/IL2 and interferon IFN-gamma/IFNG, interacts with signal transducer and activator of transcription/STAT which activate the transcription of downstream genes involved in a multitude of signals for development and homeostasis. Enhances the recruitment of CBP/p300 coactivators to STAT1 and STAT5, resulting in increased STAT1- and STAT5-dependent transcription. In response to interferon IFN-alpha, associates in a complex with signaling pathway regulator IFI35 to regulate immune response; the complex formation prevents proteasome-mediated degradation of IFI35. In complex with IFI35, inhibits virus-triggered type I IFN-beta production when ubiquitinated by ubiquitin-protein ligase TRIM21.
| Product Name: | Human NMI Recombinant Protein (N-His) |
| SKU: | GXRP11725 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | N-myc and STAT interactor, N-myc-interactor, NMI, Nmi |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Phe58-Glu307 |
| Calculated MW: | 30.64 kDa |
| UniProt: | Q13287 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
