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Human NOSIP Recombinant Protein (N-His)
Key Features

Human NOSIP Recombinant Protein (N-His) (GXRP03121)

SKU GXRP03121
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human NOSIP Recombinant Protein (N-His)

Human NOSIP Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly62-Ser295, with an N-terminal His tag. Predicted molecular weight: 28.08 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nitric oxide synthase-interacting protein (NOSIP) is a ~33 kDa protein. E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. For research use only.

Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB. Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.

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