Description
Human NPR3 Recombinant Protein (N-His)
Human NPR3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln51-Arg445, with an N-terminal His tag. Predicted molecular weight: 46.63 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Atrial natriuretic peptide receptor 3 is a ~59 kDa protein. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. For research use only.
May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production.
| Product Name: | Human NPR3 Recombinant Protein (N-His) |
| SKU: | GXRP11281 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ANP-C, ANPR-C, ANPRC, Atrial natriuretic peptide clearance receptor, Atrial natriuretic peptide receptor 3, Atrial natriuretic peptide receptor type C, C5orf23, NPR-C, NPR3, NPRC |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gln51-Arg445 |
| Calculated MW: | 46.63 kDa |
| UniProt: | P17342 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |