Description
Human NR2C2 Recombinant Protein (N-His)
Human NR2C2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg191-Pro503, with an N-terminal His tag. Predicted molecular weight: 54.6 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Nuclear receptor subfamily 2 group C member 2 (NR2C2) is a ~65 kDa protein. Orphan nuclear receptor that can act as a repressor or activator of transcription. For research use only.
An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences.
| Product Name: | Human NR2C2 Recombinant Protein (N-His) |
| SKU: | GXRP01678 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Orphan nuclear receptor TAK1, Orphan nuclear receptor TR4, TAK1, Nuclear receptor subfamily 2 group C member 2, TR4, NR2C2, Testicular receptor 4 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg191-Pro503 |
| Calculated MW: | 54.6 kDa |
| UniProt: | P49116 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
