Description
Human NSFL1C Recombinant Protein (N-His-SUMO)
Human NSFL1C Recombinant Protein (N-His-SUMO) is a recombinant protein expressed in E. coli, spanning Ser271-Thr370, with an N-terminal His-SUMO tag. Predicted molecular weight: 23.35 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. NSFL1 cofactor p47 (NSFL1C) is a ~40 kDa protein. Reduces the ATPase activity of VCP. For research use only.
Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase.
| Product Name: | Human NSFL1C Recombinant Protein (N-His-SUMO) |
| SKU: | GXRP04708 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | NSFL1 cofactor p47, p97 cofactor p47, NSFL1C, UBXN2C, UBX domain-containing protein 2C |
| Tag: | N-His-SUMO |
| Expression Host: | E. coli |
| Protein Length: | Ser271-Thr370 |
| Calculated MW: | 23.35 kDa |
| UniProt: | Q9UNZ2 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
